One of my test vehicles emptied its rear left tyre during night. In the morning I noticed a slight clonking sound from rear and steering pulling to left. I drove slowly to near service station and plugged in the compressor. Meter showed 0 bar. I was surprised as the tyre did not look empty (obviously because of its RF function).
I added air into tyre and drove the car back to dealer. We never figured out why the tyre empted during night.
Other example is from Finnish BMW forum, this picture shows that "puncture" with RF tyre does not always mean you can drive to nearest service station: